Tag Archives: meat

“Fascist Park” Recreates Thrills of Tyranny’s Golden Age

Imagine going “on safari” across Europe in 1939. Out of a nearby bunker steps none other than Adolf Hitler. He goose-steps in your direction, glowering. His little mustache twitches. Now you must choose: Siegheil! Or run!

In the latest of a new breed of extreme entertainment such as “Tough Mudder,” the biotech company Tyro-Scene has announced that it plans to recreate the twentieth century’s most vile tyrants and let them compete for resources in a naturalistic setting, while paying customers experience an afternoon of terror, repression, and the threat of genocide. Riffing on the iconic dinosaur-cloning movie series, they are calling it “Fascist Park.”

Inspired by current research into the recreation of extinct species such as the Woolly Mammoth, a company spokesman says Tyro-Scene will create scenarios that will enable customers to truly live the worst horrors of the twentieth century, including Nazism, Stalinism, apartheid, and Maoist communism. No one under 18 is permitted, and the experience is not advised for adults with heart conditions or psychological “triggers.”

idi aminFor those up to the challenge, the park promises to get your pulse racing. At any moment, Benito Mussolini, Josef Stalin, Idi Amin, Pol Pot, or even Hitler himself may pop out from behind a tree and attempt to oppress or even exterminate you.

Fascist Park will be located on nearly 10,000 desolate acres in southeastern Utah. Efforts are underway to terraform the landscape into regions resembling various tyrannical eco-systems, including central Europe, North Korea, Uganda, Libya, and Siberia. Customers will ride through the region in armored light patrol vehicles equipped with an add-on landmine protection kit and driven by a former Navy SEAL. Further protection will include issuing all customers an AK-47 rifle and requiring them to watch a fifteen-minute safety video before setting out.

The courageous will have opportunities to leave the vehicle and get “up close and personal” with some of history’s most vile human beings. Guests may be interrogated, waterboarded, or shot at. And because they may drive over land mines, pass through mists of chemical or biological weapons, or give chase, they are urged to wear loose, washable clothing and sturdy shoes.

Reanimating the twentieth century’s most fearsome tyrants may seem like mindless entertainment, but it has both scientific and historical value, the company insists.

“By recreating these dictators in a controlled but naturalistic environment, we can study the biological basis of an array of important human traits, from systematic violence to megalomania to a taste for large, dark sunglasses,” the spokesman said. “Understanding how these genes are shaped by the environment is a crucial step toward preventing genocide going forward.”

Indeed, the park will also be available to research teams who wish to study the dictators in their natural habitat. The Canadian anthropologist Woot Derbyshire, often referred to as “the Jane Goodall of messianic assholes,” plans to be first in line. “So far, I’ve had to rely on computer simulations for my work,” he said. “There’s still so much we don’t know about these sons of bitches, from their mating rituals to their grooming habits.”

Behind the scenes, Fascist Park will be an industrial research park. More than one hundred scientists will labor to maintain stocks of fresh dictators; in the wild, they inevitably impinge on one another’s plans for world domination. This leads to thrilling battles, coups, and sabotage—but it also requires regular replacements.

The park plans to open in November, 2018, with a gala opening featuring a simulated Kristallnacht. Tyro-Scene is already thinking about expanding the franchise. Action figures and plush toys are in the works, as well as customized genealogical DNA kits that will allow customers to find out which dictator they are related to. Also planned is a movie tentatively starring Ellen DeGenerate and George Cloney.

Usmanov: ‘I don’t need no stinking medal’

It’s pledge week again on National Public Radio. Imagine if Bill Gates had called in and told them, “What’s your fundraising goal for this drive? I’ll meet your target right now if you’ll call off the drive”– and NPR said, “Thanks but no thanks—we’ll see what we can get on the phones.”

Alisher Usmanov (from Wikipedia)

It turns out that’s what happened with Watson’s Nobel medal. Christie’s whispered word about the auction in several countries before the sale. Alisher Usmanov, the richest man in Russia, contacted Watson before the auction and made an offer for a financial contribution to the Lab, on the condition that Watson call off the auction, according to the latest report by Anemona Hartocollis in the New York Times (she’s had the Watson auction beat). But Watson turned down Usmanov’s offer. Hartocollis reports that Watson wanted to see how much he could get for the medal.

So Usmanov let Watson hold the auction and then bid on the medal, determined to win—but to not take home his thank-you coffee mug. As one astute Genotopia commenter observed, things have reached a strange state when a Russian oligarch takes the moral high ground.

This latest twist is vintage Watson. I can well imagine him waving away the rotund Russian and his “boring” (my imagining of Watson’s word) offer of a straight gift. I think the thrill of the gamble caught him. Crick (‘s family) got $2.1M for his. Watson was confident he could beat that. But by how much? At the auction, he watched the bidding intently, grinned broadly when it crossed $4M, and celebrated afterward.

In remarks at Christie’s before the auction, he told the audience to always “go for gold.” Silver was never enough, he said. It turns out that he had something specific in mind: he wanted not the “silver” of Usmanov’s initial offer, but the maximum gold he could get for his gold. The gamble, the risk, the competition, the publicity. The chance to take the stage once again, to rile people up, confuse them, yank the public’s chain. It became about him, not the gift.

Watson enjoys playing the scoundrel and he chose, with classic perversity, to punch a few holes in this clichéd last refuge. The reasons to undertake philanthropy are to be–or at least appear–moral, generous, selfless, humane. As the dust settles on this latest bizarre event in Watson’s long career, he ends up seeming competitive, avaricious, and childish. Of all the reasons he gave for wanting to sell the medal, the most oddly touching was the wish to rehabilitate his image. Alas, he has only reinforced it.

 

 

Having His Medal and Selling It Too

Just when we thought that the Jim Watson Nobel medal story couldn’t get any weirder, the anonymous bidder who won the medal last week is returning it.

The medal-winner revealed himself to be Alisher Usmanov, the richest man in Russia. He is paying the total $4.68 million but insists Watson keep the medal. His gesture appears to be one of generosity—but is it really?

“In my opinion,” Usmanov said, “a situation in which an outstanding scientist has to sell a medal recognising his achievements is unacceptable.” He added, “James Watson is one of the greatest biologists in the history of mankind and his award for the discovery of DNA structure must belong to him.” In short, Usmanov used the auction as a means of making a more than $4M donation to scientific research.

As I wrote the other day, it’s not true that Watson had to sell his medal—he’s hardly eating cat food. Usmanov’s stipulation that the money go to research tacitly acknowledges this fact. Triangulating—or rather, heptangulating—on Watson’s numerous statements about what he would to do with the money, he probably intended to keep a chunk of it, but give most of it away. Although he mused about giving to each of the schools that were primary to his education, experience suggests that most will go to Cold Spring Harbor Laboratory (always his favorite charity). We—or anyway I—will be watching for an announcement in the near future about the endowment of a new Cold Spring Harbor fellowship, probably for young scientists.

So much for the Hockney, though.

But there remains the question of whether Usmanov is doing Watson a favor by returning the medal. Usmanov has upstaged Watson, foiling any effort for Watson to rehabilitate his image through major charitable giving. Watson still has the $600k from the sale of the documents, which went to a different bidder, but that is a small fraction of what his total gift could have been.

Is Usmanov’s gesture a well-intentioned blunder or is it philanthropic one-upsmanship? By returning the medal, Usmanov is simultaneously contributing to scientific research and throttling Watson’s effort to do the same.

If, on the other hand, Watson’s only intention was to raise money for the Lab, then he gets to have his medal and sell it too. I think we can dispense with the prospect of his turning around and selling it again—that seems too cheeky even for Watson. But who knows? Every time he goes out for a long one, he seems to do a double reverse.

The one safe conclusion is that deterministic explanations rarely fit Watson’s actions. A single motivation almost never fully accounts for what he says. Darwin knows, Watson says much that deserves criticism. But anyone who takes his remarks at face value misunderestimates him, is more interested in self-congratulatory castigation than genuine understanding, or some combination of the two.

DNA Supplements May Be Secret of Longer, Healthier Life

Tired? Forgetful? Feeling old before your time? Forgetful? Maybe it’s your DNA—or lack of it.

DNA-based alternative medicine is one of the fastest growing health fields today. Combining the marketing strengths of science, health, and religion, it’s no wonder that researchers are stocking the shelves and lining their pockets with a variety of DNA supplements and diagnostics. Here are some of the most exciting products and findings.

Puritan's PrideA diet rich in DNA—and its molecular cousin, RNA—is correlated with improved performance across a wide range of activities, both physical and mental, and could help stave off the effects of aging. Results of a bold new study from Kashkow University’s School of DNA and Medicine, expected to begin next year, were announced yesterday. They have been called a “breakthrough” and a “game-changer” by some of the leading scientists on the proposed study.

Dr. Cyrus Tosine, a lead researcher on the study, said that supplemental DNA and RNA could be of particular benefit to patients suffering from low energy, poor muscular strength and stamina, pain and stiffness in the joints, forgetfulness, and an inability to concen

The general result should come as no surprise, Tosine says. “DNA and RNA operate at the core of life,” he notes. “Supplemental RNA and DNA promote cellular integrity.” Independent research does confirm that the absence of RNA and DNA negatively affects cells’ ability to survive, which could be considered a form of integrity. Further, Tosine pointed out, nucleic acid activity is halted by cell death. “And when your cells die, you die,” he observed. DNA, he concludes, is related to aging. “QED.”

The research uses a sophisticated new analytical technique called “meta-meta-analysis,” which pools the results of many studies that pool the results of many studies. This gives the method such great statistical power that it can find a correlation between any two variables. Thus, it is already possible to say with confidence that DNA intake is positively correlated with all major indicators of health—and negatively correlated with a variety of diseases.

The research was hailed by the plastic surgeon Dr. Vincent C. Giampapa, M.D., F.A.C.S., one of the most prominent members of this exciting new field. “DNA is our life source,” he confirmed.
Recognizing a potential market in anxious new mothers and covering both the scientific and religious bases, one company is developing a line of infant probiotics called “DNA Miracles.” Their advantage, she says, is that “with DNA Miracles Probiotics Extra, you can rest easy knowing that you’re providing your child one of the most complete children’s probiotic and prebiotic formulas on the market today.”

Magnum DNAAthletes, too, are recognizing the benefits of upping their intake of what double helix co-discoverer Francis Crick called the “secret of life.” DNA is being mixed with branched-chain amino acids (BCAAs)—some of the building blocks of protein—to create potent muscle-building supplements. An Australian company offers a patented “coded DNA amino acid BCAA,” which contains “the perfect coded DNA amino acid sequence.” The sequence, of course, is not only proprietary but classified, lest it fall into the hands of an evil mastermind determined to clone a race of LeBron Jameses crossed with Olga Korbuts.
DNA Repair Cream

Other work centers on DNA repair, a well-established field of science. Dr. Giampapa, M.D., F.A.C.S., is author of over 700 studies showing the benefits of improving DNA with his patent formulas. “Just improving a small percentage of our total DNA can make a major difference in the quality of our health, well being and longevity.” Dr. Giampapa, M.D., F.A.C.S. says. Science is still learning how small a percentage can make a major difference, and what in the name of Watson and Crick “improving” your DNA could mean.

Where does it come from?

Not all DNA is created equal. Some of the highest quality DNA is extracted from freeze-dried lamb placenta, say some experts. Dr. Rad Bitchen, of Woohoo Pharmaceuticals, explains: “Studies have supported that sheep placenta is one of the richest source of nutrients.” Two capsules of their DNA/RNA supplement contain over five miles of nucleic acid—500 times the recommended daily allowance, set last week by Bitchen himself.

wohoo lamb placenta dnaAnimal rights’ groups, however, have protested the freeze-drying of lambs. A spokesorganism for PETNA (People for the Ethical Treatment of Nucleic Acids) notes that even in a wool coat, the young ovines must get the shivers during the process.

PETNA and others promote the use of “cruelty-free” DNA. Woohoo’s DNA also contains “marine protein,” which, Bitchen insists, is “like wicked delicious.” He emphasizes that no Marines are harmed in his process. Another company, Anathema Nucleoceuticals, makes a line of DNA-based condiments. Their biggest seller is Guano Butter, made from bat guano and olive oil. Anathema’s literature says it is delicious on whole grain toast or Ak-Mak crackers. Yet some object to DNA collected from any higher animals.

“No nuclear membrane, no problem,” says Ariadne Fishnet, of Portland, Oregon. Fishnet is a freelance farmer of sustainable E. coli, a bacterium normally found in the human gut. Extracting the DNA from bacteria is completely painless, she says, even though it eviscerates the organism. “At first we used only wild-caught bacteria, because that sounded better. But it turned out to be economically unpractical, as well as kind of gross. We have a new model of sustainable bacteria farming. All our bacteria are free-range, non-GMO, and antibiotic-free.”

Skeptics

Swanson RNA & DNANevertheless, not everyone is convinced of the value of megadoses of DNA. Dr. Ron Swanson, of the University of California at Boulder, believes that prokaryotic nucleic acid is at best worthless and perhaps damaging. “The highest quality DNA comes from steak and cigars,” he says. Further, he continues, it is not the quantity but the “balance” between DNA and RNA that provides the key to health. “Our studies show that RNA/DNA imbalance is the root cause of a variety of symptoms,” he said. “If you feel fatigue, weakness, muscle and joint stiffness, memory loss, or lack of ability to concentrate, restoring the correct balance has been shown absolutely equivocally to sometimes help stuff,” he said.

Drs. Kathleen, Elaine, and Mary, of the Natural Healthcare Ministries Research Center and Salon in Credulity, Wisconsin, believe that massive doses of DNA and RNA constitute a “one size fits all” approach that is out of harmony with what makes us all special. DNA medicine should be personalized, “Because we’re all people,” noted Mary. “Except for the sheep,” Elaine chimed in. “Yea but they’re frozen,” Mary replied. “Shut up,” snapped Elaine.

Kathleen continued, “Homeopathic energy DNA testing is based on the principle that everything in nature, even substances that do not move, gives off energy as a vibration.” Any foreign substance entering the body, she said, may have an irritating effect on the body, “because of the vibrations.” Their method, Sound Therapy On Nucleic acid Energy Depletion (STONED), is to “ test this energy (your DNA) by testing your hair.” They then correct the vibrations using a variety of cellular actualization techniques. They also offer styling and manicures, half off on Tuesday mornings.

In spite—or perhaps because— of its controversial nature, DNA medicine is clearly on the rise. All experts agree on one point: everyone should limit their intake of food that contains no DNA. Examples include processed sugar, high-fructose corn syrup, lard, and Chicken McNuggets.

 

 

 

Suicide genes? Just kill me now

I’m in the middle of writing a grant, so I’ll have to leave it as an exercise for the reader to think about the implications of genetic profiling of potential suicides, as hinted at in this story over at Forbes. Six genes predict suicides among those with bipolar disorder. As attentive followers will guess, my criticism is not that such correlations are impossible—it’s that they are inevitable.

Manet’s The Suicide

Hmm, possibly there’s a future piece on why a conservative money mag seems to be emerging as a bastion of the new genetic determinism…

DNA Ink

We’ve been pretty serious for a while, which always makes me a little edgy. And “tattoos” or some version thereof continues to be one of the biggest search terms for this blog. So, to raise the font size of “tattoos” in the tag cloud, I’ve put together a gallery of eye candy.

In their 1994 book, The DNA Mystique, Susan Lindee and Dorothy Nelkin write that “habitual images and familiar metaphors…provide the cultural forms that make ideas communicable.” The double helix is the scientific icon of our age—much like the Bohr atom was during the Cold War. Putting it on your body identifies you with science, with biotechnology, with life. It is also just a stone beautiful image, which works in a line, say down your spine, wrapped around a biceps or ankle, or curving sinuously just about anywhere. The best collection of science-themed tattoos of course is Carl Zimmer’s “Science Tattoo Emporium.” Many of these were borrowed from his archive, so a big hat-tip (tat-hip?) to him. I have the hardcover version Science Ink prominently displayed on my coffee table. Others drawn from elsewhere around the web. Click the picture to open the original url.

tree-dna

A DNA riff on the Darwinian image of the “tree of life.” But it of course also reminds me of the eugenics tree…

eugenics-tree

Foot tattoos are hard. Here's a cute rendition of unwinding DNA that flows nicely with the anatomy.

Foot tattoos are hard. Here’s a cute rendition of unwinding DNA that flows nicely with the anatomy.

Not the best execution of the image (no major and minor grooves), but a neat black-light effect that reminds me of fluorescent labeling.

Not the best execution of the image (no major and minor grooves), but a neat black-light effect that reminds me of fluorescent labeling.

Just. Wow.

Just. Wow.

All right, I admit I'm wondering whether this represents bacterial DNA (and is therefore circular).

All right, I admit I’m wondering whether this represents bacterial DNA (and is therefore circular).

An interesting “biomechanical” visual effect.

Here artist Jason Stomber has woven the double helix into a full sleeve.

Here artist Jason Stomber has woven the double helix into a full sleeve.

Clever use of the DNA icon by a pair of twin sisters. Of course, when they line them up, they become prokaryotes.

Clever use of the DNA icon by a pair of twin sisters. Of course, when they line them up, they become prokaryotes.

 

 

The gene for hubris


A recent post by Jon Entine on the Forbes website leads with a complimentary citation of my book– and then goes on to undermine its central thesis. He concludes:

Modern eugenic aspirations are not about the draconian top-down measures promoted by the Nazis and their ilk. Instead of being driven by a desire to “improve” the species, new eugenics is driven by our personal desire to be as healthy, intelligent and fit as possible—and for the opportunity of our children to be so as well. And that’s not something that should be dismissed lightly.

Well, first of all, as the recent revelations of coerced sterilization of prisoners in California shows, “draconian, top-down” measures do still occur. Genetics and reproduction are intensely potent, and wherever we find abuse of power we should be alert to the harnessing of biology in the service of tyranny.

Second, there’s more than one kind of tyranny. Besides the tyranny of an absolute ruler, perhaps the two most potent and relevant here are the tyranny of the commons and the tyranny of the marketplace. The fact that they are more subtle makes them in some ways more dangerous. The healthcare industry does much good in the world, but it is naive to treat it as wholly benign.

Further, putting human evolution in the hands of humans, means accepting long-term consequences for short-term goals. The traits we value–health, intelligence, beauty–are the result of the action of many genes interacting with each other and with a dynamic environment. The entire system is contingent, inherently unpredictable. Yet we treat it as simple and deterministic. Until now, technology has been the major obstacle to guiding human evolution. It may be that now the major obstacle is our reasoning ability, our capacity for grasping contingency and probability and change. We’re tinkering with the machinery of a system whose complexity is still unfolding before us. The probability of unforeseen consequences is 100%. The only question is how severe they will be. We will only know in retrospect.

If we now have the tools to meaningfully guide our own evolution–as eugenicists have always wanted to do–we cannot take a blithe and Panglossian attitude. We have to be alert to the risks and take them seriously. That is not traditionally science’s strong suit. The public face of science is sunny, optimistic, fun. It strides boldly into the future, laughing and making striking promises. The industries behind science and health are wealthy and politically powerful. Not everything they do is benign.

To be a critic of that public-relations machine–of hype, in other words–is not to be a critic of health or knowledge or progress. Genetic science has the potential to bring us enormous benefits in health and well-being, and as they do, I stand in line with my fellow humans for my fair share. But that science also carries huge and unforeseeable risks, the root of which, perhaps, is arrogance. It’s one whose consequences are painfully evident in the historical record.